State Street SPDR S&P Pharmaceuticals ETF (XPH): outlook, holdings and fees
State Street SPDR S&P Pharmaceuticals ETF (XPH) is an exchange-traded fund and is managed by State Street Investment Management. The expense ratio is 0.35% and the yield is 0.41%. The ten largest holdings are 22% of the fund.
Fund data as of Oct 14, 2026 · Price Nov 2, 2026
ATLAS view on XPH
| Last price | $63.80 (-1.5%) |
|---|---|
| ATLAS chance of a higher price in 1 month | 53% |
| Likely 1-month range (50%) | $61.61 – $66.57 |
| Normal 1-day range (±1σ) | ±1.3% |
| Distribution yield | 0.41% |
ATLAS probabilities use the same calibrated model as every stock page. A fair value is shown for companies, not funds; the holdings below link to the fair value of each company.
XPH fund facts
| Issuer | State Street Investment Management |
|---|---|
| Theme | Healthcare |
| Assets under management | $461M |
| Expense ratio | 0.35% |
| Number of holdings | 50 |
| Portfolio turnover | 51% |
| Inception | Jun 19, 2006 |
| Exchange | NYSE |
In seeking to track the performance of the S&P Pharmaceuticals Select Industry Index (the index), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the pharmaceuticals segment of the S&P Total Market Index (S&P TMI).
XPH top holdings
| Holding | Sector | Weight |
|---|---|---|
| Xeris Pharmaceuticals Inc XERS | Healthcare | 2.62% |
| Veradermics, Incorporated MANE | Healthcare | 2.55% |
| Pacira BioSciences, Inc. PCRX | Healthcare | 2.52% |
| Amneal Pharmaceuticals, Inc. Class A Common Stock AMRX | Healthcare | 2.27% |
| Viatris Inc VTRS | Healthcare | 2.17% |
| Perrigo Company PLC PRGO | Healthcare | 2.07% |
| Eli Lilly and Company LLY | Healthcare | 2.05% |
| Ligand Pharmaceuticals Incorporated LGND | Healthcare | 1.99% |
| Corcept Therapeutics Incorporated CORT | Healthcare | 1.99% |
| ANI Pharmaceuticals Inc ANIP | Healthcare | 2.11% |
Holdings with an ATLAS page link to their probability range, fair value and earnings calendar.
XPH sector breakdown
| Sector | Weight |
|---|---|
| Healthcare | 100.0% |
By region: North America 100.0%.
XPH returns and risk
| Year to date | +15.0% |
|---|---|
| 1 year | +36.4% |
| 3 years (annualised) | +20.5% |
| 5 years (annualised) | +7.4% |
| 10 years (annualised) | +4.9% |
| Volatility (3 years) | 20.5% |
| Sharpe ratio (3 years) | 0.76 |
Past returns do not guarantee future results.
XPH: frequently asked questions
What does XPH invest in?
State Street SPDR S&P Pharmaceuticals ETF invests in a portfolio of securities. Its largest holdings are Xeris Pharmaceuticals Inc (2.6%), Veradermics, Incorporated (2.5%), Pacira BioSciences, Inc. (2.5%), Amneal Pharmaceuticals, Inc. Class A Common Stock (2.3%), Viatris Inc (2.2%).
What is the XPH expense ratio?
0.35% a year: about $35.00 for every $10,000 invested.
What is the XPH dividend yield?
0.41%. ATLAS does not hold the exact distribution dates for ETFs.
Will XPH go up?
Nobody can know. The ATLAS model puts the chance of a higher price in one month at 53%, with a likely range (50%) of $61.61 to $66.57 from $63.80 today. It is a probability, not a prediction.
How has XPH performed?
Year to date +15.0%, one year +36.4%, three years +20.5% a year, five years +7.4% a year. Past returns do not guarantee future results.
Similar ETFs: Healthcare
- State Street Health Care Select Sector SPDR ETF (XLV)
- Vanguard Health Care ETF (VHT)
- iShares Global Healthcare ETF (IXJ)
- iShares U.S. Healthcare ETF (IYH)
- iShares U.S. Medical Devices ETF (IHI)
- Fidelity MSCI Health Care Index ETF (FHLC)
- iShares U.S. Pharmaceuticals ETF (IHE)
- First Trust Health Care AlphaDEX Fund (FXH)
Educational information, not investment advice. Disclaimer